江南体育-欧盟评估非转基因桔绿木霉菌株HBI

欧盟评估非转基因桔绿木霉菌株HBI-TX01出产的内切-1,4-β-木聚糖酶的平安性时候：2024-12-13 11:00来历：食物火伴网作者： 泽夕 焦点提醒：2024年12月12日，欧盟食物平安局就一种食物酶内切-1,4-β-木聚糖酶（endo-1,4-β-xylanase）的平安性评价发布定见。 食物火伴网讯 2024年12月12日，欧盟食物平安局就一种食物酶内切-1,4- -木聚糖酶（endo-1,4- -xylanase）的平安性评价发布定见。 据领会，这类食物酶是由非转基因桔绿木霉菌株HBI-TX01出产的，旨在用在4种食物制造进程。 颠末评估，专家小组认为，在预期的利用前提下，不克不及解除经由过程饮食接触引发过敏反映的风险，但这类环境产生的可能性很低。按照所供给的数据，小组得出结论，该食物酶在预期的利用前提下不会引发平安问题。部门原文报导以下： The food enzyme endo-1,4- -xylanase (4- -d-xylan xylanohydrolase; EC 3.2.1.8) is produced with Trichoderma citrinoviride strain HBI-TX01 by HBI Enzymes Inc. The food enzyme is free from viable cells of the production organism. It is intended to be used in four food manufacturing processes. Since residual amounts of food enzyme total organic solids (TOS) are removed in two food manufacturing processes, dietary exposure was calculated only for the remaining two processes. It was estimated to be up to 1.488 mg TOS/kg body weight (bw) per day in European populations. Genotoxicity tests did not indicate a safety concern. The systemic toxicity was assessed by means of a repeated dose 90-day oral toxicity study in rats. The Panel identified a no observed adverse effect level of 1101 mg TOS/kg bw, the highest dose tested, which when compared with the estimated dietary exposure, resulted in a margin of exposure of at least 740. A search for homology of the amino acid sequence of the food enzyme to known allergens was made and no match was found. Known sources of food allergens were used in the manufacturing process. The Panel considered that the risk of allergic reactions upon dietary exposure to this food enzyme cannot be excluded, but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use. 本文由食物火伴网食物资讯中间编纂，供网友参考，有任何疑问，请联系news@foodmate.net。