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欧盟评估转基因枯草芽孢杆菌菌株AR-153出产的内切-1,4-β-木聚糖酶的平安性时候:2024-12-17 10:29来历:食物火伴网作者: 泽夕 焦点提醒:2024年12月13日,欧盟食物平安局就一种食物酶内切-1,4-β-木聚糖酶(endo-1,4-β-xylanase)的平安性评价发布定见。 食物火伴网讯 2024年12月13日,欧盟食物平安局就一种食物酶内切-1,4- -木聚糖酶(endo-1,4- -xylanase)的平安性评价发布定见。 据领会,这类食物酶是由转基因枯草芽孢杆菌菌株AR-153出产的,旨在用在4种食物制造进程。 颠末评估,专家小组认为,在预期的利用前提下,不克不及解除经由过程饮食接触引发过敏反映的风险,但这类环境产生的可能性很低。按照所供给的数据,小组得出结论,该食物酶在预期的利用前提下不会引发平安问题。部门原文报导以下: The food enzyme endo-1,4- -xylanase (4- -d-xylan xylanohydrolase; EC 3.2.1.8) is produced with the genetically modified Bacillus subtilis strain AR-153 by AB Enzymes GmbH. The genetic modifications do not give rise to safety concerns. The production strain meets the requirements for the qualified presumption of safety (QPS) approach. The food enzyme is free from viable cells of the production organism and its DNA. It is intended to be used in four food manufacturing processes. Since residual amounts of total organic solids (TOS) are removed during one food manufacturing process, dietary exposure was only calculated for the remaining three processes. Exposure was estimated to be up to 0.463 mg TOS/kg body weight per day in European populations. Given the QPS status of the production strain and the absence of concerns resulting from the food enzyme manufacturing process, toxicity tests were considered unnecessary by the Panel. A search for homology of the amino acid sequence of the food enzyme to known allergens was made and no match was found. The Panel considered that the risk of allergic reactions upon dietary exposure cannot be excluded, but the likelihood is low. based on the data provided, the Panel concluded that this food enzyme does not give rise to safety concerns, under the intended conditions of use. 本文由食物火伴网食物资讯中间编纂,供网友参考,有任何疑问,请联系news@foodmate.net。